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Phosphoribosyl-ATP diphosphatase : ウィキペディア英語版 | Phosphoribosyl-ATP diphosphatase
In enzymology, a phosphoribosyl-ATP diphosphatase () is an enzyme that catalyzes the chemical reaction :1-(5-phosphoribosyl)-ATP + H2O 1-(5-phosphoribosyl)-AMP + diphosphate Thus, the two substrates of this enzyme are 1-(5-phosphoribosyl)-ATP and H2O, whereas its two products are 1-(5-phosphoribosyl)-AMP and diphosphate. This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is 1-(5-phosphoribosyl)-ATP diphosphohydrolase. Other names in common use include phosphoribosyl-ATP pyrophosphatase, and phosphoribosyladenosine triphosphate pyrophosphatase. This enzyme participates in histidine metabolism. It employs one cofactor, H+. ==Structural studies==
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes , , , and .
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